NLR Family, Pyrin Domain Containing 12 (NLRP12) (N-Term) Peptide
NLRP12
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5512640
Aperçu rapide pour NLR Family, Pyrin Domain Containing 12 (NLRP12) (N-Term) Peptide (ABIN5512640)
Antigène
NLRP12
(NLR Family, Pyrin Domain Containing 12 (NLRP12))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NLRP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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Sujet
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This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
Alias Symbols: NLRP12,NALP12,PYPAF7,RNO,
Protein Size: 1061 -
ID gène
- 91662
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NCBI Accession
- NP_653288
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UniProt
- P59046
Antigène
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